Zentraub Bortz (Boris Boric) was a late inclusion for the second leg at the Allianz Arena, and he was not helped by the fact that he was replaced by Naby Keita.
The former Juventus midfielder started the game, but was unable to hold on for a goal in his second appearance of the season, with Dortmund losing 4-2 at home to Borussia Dortmund on Sunday.
In the first leg, Keita scored his first goal of the Bundesliga season and scored his third and fourth of the campaign in the 1-0 win.
Borussia are currently second, five points behind leaders Bayern Munich.
The away leg will be played on March 20.